Factors identified for poor long-term survival in RT-treated patients with oropharyngeal cancer

Source: www.cancertherapyadvisor.com Author: Susan Moench, PhD, PA-C Specific patient- and treatment-related factors were identified as potential survival detriments for patients with a history of oropharyngeal cancer (OPC) who received radiation therapy (RT) and were alive for at least 5 years following diagnosis, according to findings from a retrospective database review published in Cancer. Specifically, older age at diagnosis (≥55 years; standardized mortality ratio [SMR], 3.68), status as a current or former smoker (SMR, 3.28 vs 7.43), and the presence of tonsil (SMR, 4.39) or base of tongue tumors (SMR, 3.10) or category T4 tumors (SMR, 5.43) correlated with a higher risk for death. Previous research has demonstrated that patients with head and neck cancers who remain recurrence-free for 5 years following diagnosis have a very low risk of disease recurrence. However, less is known about the conditional long-term survival of this group of patients, represented by the 2-, 5- and 10-year overall survival (OS) probabilities for those without evidence of disease recurrence 5-years post-diagnosis. Furthermore, patient, disease-, and treatment-related factors associated with long-term survival in these patients are also not well understood. Of the 1699 patients included in this analysis, all were newly diagnosed with squamous cell carcinoma OPC between 1980 and 2012, had no cancer event for the 5 years that followed OPC diagnosis, and had been treated with RT without surgery at the University of Texas MD Anderson Cancer Center in Houston, Texas. Baseline characteristics of this patient cohort included a median age of 60 years. Most of [...]

Gwynn’s death sparks dip debate

Source: www.trentonian.com Author: Nick Peruffo The death of San Diego Padres icon Tony Gwynn due to oral cancer Monday resonated across the baseball world — including the Trenton Thunder clubhouse. In addition to being a person tragedy for the Gwynn family, the news also put a renewed focus on the use of chewing tobacco in baseball. Officially, tobacco in any form has been banned in the minor leagues since 1993. If caught with chewing tobacco on the field, players face a $300 fine, while managers are docked $1,000. Away from the field, however, it is clear that some players continue to dip. “There are so many guys that do it,” said catcher Tyson Blaser, who does not use chewing tobacco. “It’s very common in the major leagues, and even though obviously in the minor leagues you are not supposed to do it, some people don’t adhere to that. To see an icon like (Gwynn) lose his battle with cancer because of a habit a lot of people do, I assume it’d be eye opening to some people.” Gwynn, who was just 54, blamed his cancer on dipping tobacco. Despite that, manager Tony Franklin conceded that while the coaching staff does its best to dissuade players from using, what they do on their own time is ultimately their own decision. “We encourage them not to do it, but they are adults with choices to make,” Franklin said. “The choices they make could be very beneficial and save their lives, so we [...]

Facing the facts: HPV-associated head and neck cancers get a second look

Source: www.curetoday.com Author: Charlotte Huff Kevin Pruyne knew he didn’t fit the stereotype of a hard drinker or heavy smoker who one day develops an oral cancer. The 52-year-old mechanic had been working a three-week stint in a remote section of northern Alaska, repairing trucks on an oil field, when he noticed a hard lump beneath his jaw while shaving. For nearly three months, as Pruyne was prescribed antibiotics for a possible infection and then later shuttled between physician specialists, he kept hearing the same thing: the lump could not be cancer. Pruyne only occasionally consumed alcohol and had never smoked. His wife, Kathy, began researching her husband’s symptoms, which included repetitive throat clearing, a nagging sensation that something was lodged in his throat and ringing in his ears. And the lump, which looked like the top half of an egg, felt solid to the touch. This wasn’t some inflamed lymph node from a lingering head cold, Kathy Pruyne says. “He had every symptom [of cancer], but nobody would listen to me.” Pruyne received a diagnosis of stage 4 oral cancer, which started with a tumor at the base of his tongue. He had already begun chemotherapy when he learned that researchers had discovered an association between the human papillomavirus (HPV) and increasing rates of oropharyngeal cancers. He asked that his tissue be tested; the results came back positive. Pruyne says he wanted to know whether his cancer was caused by HPV because “the prognosis is considerably better with HPV-positive cancer.” [...]

New cigarette packs will shock

Source: www.adelaidenow.com.au Author: Samantha Maiden Shocking new warnings for cigarette packets will feature sick babies, a dying man and a naked smoker with a colostomy bag. Health Minister Nicola Roxon launched the new health warnings yesterday and confirmed plans to stamp tobacco products with the images from July next year. And the giant warnings will cover 75 per cent of cigarette packets - rather than the current 30 per cent. The new warnings will appear at the same time as world-first plain packaging that will force manufacturers to sell cigarettes in plain, olive-brown packets. The new plain-packing rules will ban branding of any form, removing the last forum for tobacco advertising in Australia. Other images include horrific images of a man dying of lung cancer with his eyes rolled back. A rotting, gangrenous foot and images of a man with tongue cancer are also included. Ms Roxon launched the discussion paper, conceding they were "striking and confronting reminders of the death and disease that tobacco brings." She said the shock tactics were a proven, effective way of helping people to kick the habit. "Seeing the heartbreaking harm that can be caused to an unborn baby or the horrific effects of cancer is a shocking reminder that quitting smoking is one of the best things that someone can do to improve their health," she said. "And 15,000 Australians die from tobacco each year. That's too many families mourning a loved one and why the Government is acting to protect the health [...]

2011-09-19T19:14:30-07:00September, 2011|Oral Cancer News|

Disadvantages of using chewing tobacco to quit smoking

Source: www.helium.com Author: Dawn Hawkins If you are a smoker who is trying to quit smoking, there are several ways in which you might attempt to attain the goal. Chewing tobacco might seem like one of the best answers to your problem. The goal is to stop the smoke from going into your lungs, right? That is partially true. There are many advantages of using chewing tobacco to quit smoking, but there are great disadvantages to it also. Disadvantages of using chewing tobacco to quit smoking: Teeth- Your teeth become discolored much faster when you chew tobacco in order to try to quit smoking. Your teeth will suffer discoloring when you smoke cigarettes, but chewing tobacco comes into direct contact with the tooth's surface making them more susceptible to staining. Spitting- When you chew tobacco, you also have to spit it somewhere. This can be a problem if someone takes away the container that you are spitting in. It is also not a very attractive thing to do. You have to carry something around with you at all times that contains your already chewed tobacco and your spit. That is another thing that is definitely not attractive. Accidents- When you have a bottle that you are using to spit the tobacco into, there is a good chance your or someone else will accidentally drink the mixture thinking it is something else. chewing tobacco has a very foul taste when combined with spit. It is also very unhealthy to swallow. That [...]

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