FDA to review application to modify health warning on Altria subsidiary’s smokeless tobacco product

Source: www.richmond.com Author: staff The U.S. Food and Drug Administration will review a request from an Altria Group Inc. subsidiary that wants to make the claim that a smokeless tobacco product is less dangerous than cigarettes. U.S. Smokeless Tobacco Co. said Friday that the FDA has agreed to do a substantive review of its “modified risk” application for Copenhagen Snuff Fine Cut. The company submitted the request for review earlier this year. The snuff company wants to be able to use the claim “If you smoke consider this: Switching completely to this product from cigarettes reduces risk of lung cancer.” The FDA requires smokeless tobacco products to carry statements that warn about the risk of mouth cancer, gum disease, tooth loss and addiction and that the product is not a safe alternative to cigarettes. The warnings are to be randomly rotated on packaging. “We filed this application because we think adult smokers looking for potential reduced risk alternatives to cigarettes should have accurate information about the relative risks of Copenhagen Snuff,” Joe Murillo, Altria Client Services senior vice president for regulatory affairs, said in a statement. The FDA defines modified risk tobacco products as tobacco products that are sold or distributed for use to reduce harm or the risk of tobacco-related disease associated with commercially marketed tobacco products. In the review process, the FDA’s Tobacco Products Scientific Advisory Committee vets the scientific claims and makes a recommendation. The FDA has reviewed more than 30 modified risk applications from tobacco companies [...]

2018-09-16T06:48:11-07:00September, 2018|Oral Cancer News|

E-cigarettes and smokeless tobacco can put you at a greater risk of oral cancer, says study

Source: www.thehealthsite.com Author: Sreemoyee Chatterjee Not just cigarette smokers, those smoking e-cigarettes as well as consuming smokeless tobacco like chewing tobacco and more are at greater risk of developing oral cancer, shows a recent study conducted by University of California. In case you think only cigarette smokers are at a higher risk of getting oral cancer, you are widely mistaken. A recent study has found that a wide majority of non-cigarette tobacco users as well those using electronic cigarettes are exposed to considerable level of carcinogen, as much as a cigarette user is exposed to. Not just that, shockingly smokeless tobacco users were found at a greater exposure to tobacco-specific nitrosamines (TSNA). The study has been conducted by the scholars from University of California, San Francisco. Starting from cigarettes to cigar, waterpipes, pipes, marijuana containing cigar to smokeless products like moist snuff, chewing tobacco, e-cigarettes, snus and other nicotine replacement products can increase your chance of getting oral cancer, revealed the study. What is Oral cancer? Belonging to the head and neck cancer group, oral cancer is a type of cancer that grows in mouth or throat tissues and mostly hit the squamous cells of your mouth, tongue and lips. Oral cancer can of several types – lip cancer, tongue cancer, cancer in the inner lining of your cheek, gums, floor of the mouth and hard and soft palate. It is important to go to a dentist for a biannual check-up for early detection of oral cancer, experts say. Due [...]

Smokeless tobacco, snuff, chew not safe substitutes for cigarettes

Source: www.bnd.com Author: staff As many people are aware, the use of any type of tobacco can lead to major health risks. Many individuals think using smokeless tobacco or chew can be a safe substitute for cigarettes. A mock model of how dangerous and destructive tobacco products, specifically smokeless tobacco, can be to someone’s health and well-being. Navy photo by Douglas H. Stutz, Naval Hospital Bremerton Public Affairs Tobacco companies often lead people to believe this; however, this is not true. There is no proof that any smokeless tobacco products help smokers quit smoking. Smokeless tobacco has four times the amount of nicotine than a cigarette and also contains 30 chemicals known to cause cancers. A few of these cancers include mouth, tongue, cheek, and gum cancer. Additionally, cancer can be found in the esophagus and pancreas. Along with these health risks there are other problems, including mouth and teeth problems and tooth loss. Many studies have shown that high rates of leukoplakia in the mouth were found where individuals hold the chew. Leukoplakia is a white patch in the mouth that could potentially turn into cancer. The white patches, sometimes called sores, within the mouth cannot be scraped off but usually do not cause pain. The longer the use of oral tobacco, the more prone an individual is to develop leukoplakia. Stopping tobacco use usually allows leukoplakia to heal, however, treatment may be needed if there are signs of early cancer. Along with these issues, there are [...]

2017-11-27T08:15:41-07:00November, 2017|Oral Cancer News|

Smokeless Tobacco Use and the Risk of Head and Neck Cancer: Pooled Analysis of US Studies in the INHANCE Consortium.

Source: www.pubmed.gov Author: Wyss AB, Gillison ML, Olshan AF Abstract Previous studies on smokeless tobacco use and head and neck cancer (HNC) have found inconsistent and often imprecise estimates, with limited control for cigarette smoking. Using pooled data from 11 US case-control studies (1981-2006) of oral, pharyngeal, and laryngeal cancers (6,772 cases and 8,375 controls) in the International Head and Neck Cancer Epidemiology (INHANCE) Consortium, we applied hierarchical logistic regression to estimate odds ratios and 95% confidence intervals for ever use, frequency of use, and duration of use of snuff and chewing tobacco separately for never and ever cigarette smokers. Ever use (versus never use) of snuff was strongly associated with HNC among never cigarette smokers (odds ratio (OR) = 1.71, 95% confidence interval (CI): 1.08, 2.70), particularly for oral cavity cancers (OR = 3.01, 95% CI: 1.63, 5.55). Although ever (versus never) tobacco chewing was weakly associated with HNC among never cigarette smokers (OR = 1.20, 95% CI: 0.81, 1.77), analyses restricted to cancers of the oral cavity showed a stronger association (OR = 1.81, 95% CI: 1.04, 3.17). Few or no associations between each type of smokeless tobacco and HNC were observed among ever cigarette smokers, possibly reflecting residual confounding by smoking. Smokeless tobacco use appears to be associated with HNC, especially oral cancers, with snuff being more strongly associated than chewing tobacco. © The Author 2016. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. *This news story [...]

2016-10-31T14:31:13-07:00October, 2016|Oral Cancer News|

Smokeless tobacco use on the rise among high school athletes

Source: kimt.com Author: Jeron Rennie A new Centers for Disease Control and Prevention (CDC) report shows a trend they don’t want to see. A Morbidity and Mortality Weekly Report (MMWR) shows that from 2001-2013, smokeless tobacco use increased significantly among high school athletes, but not with non-athletes. The report also found there was lower use of combustible tobacco products among athletes than non-athletes. The CDC said that could be due, in part, to an awareness of the negative consequences on athletic performance. However, they say the use of smokeless tobacco suggests they find those products as being harmless. “When you see it in the media and you see all those athletes that you’re looking up to as a younger student and trying to reach some of the goals that they’ve reached,” said Freeborn County Drug-Free Coalition Prevention Coordinator Lana Howe. “It definitely plays a large impact on you as a youth.” The CDC said using smokeless tobacco can, however, adversely impact athletic performance and lead to disease and early death since they contain nicotine, toxins and carcinogens. Several athletes with a history of smokeless tobacco use have been diagnosed with, or died from, oral cancer.

2015-09-13T15:20:13-07:00September, 2015|Oral Cancer News|

Salivary gland cancers rare, but sometimes deadly

Source: articles.baltimoresun.com Author: Andrea K. Walker Professional baseball great Tony Gwynn Sr., also known as Mr. Padre, died last month of salivary gland cancer, which he believed was caused by years of using smokeless chewing tobacco. The cancer is a rare form that begins in any of the salivary glands in the mouth, neck or throat. Two adults in 100,000 are diagnosed with salivary gland cancer each year. The chances of survival drop if the cancer has spread to other parts of the body. Dr. Patrick K. Ha, with Johns Hopkins Head and Neck Surgery at Greater Baltimore Medical Center, says new types of treatments and therapies are in the works to treat the disease. What is salivary gland cancer and how common is it? Salivary gland cancers are a diverse group of rare malignancies that can involve any of the major salivary glands (the parotid, submandibular and sublingual) or minor salivary glands, which are found within the lip, palate, tongue base, nasal cavity or sinuses. There are numerous different cancers that may arise from the salivary glands, and these may behave differently based on their cell of origin. What causes it, and who is more likely to get it? Little is known about the causes of salivary gland cancers. Unlike the more common head and neck cancers, which have a clear association with smoking, drinking or even the human papillomavirus (HPV), salivary gland cancers do not have such strong associations. There may be a link between significant radiation exposure (i.e., treatment [...]

The danger in smokeless tobacco products

Source: www.observer.ug (Uganda, Africa) Author: Racheal Ninsiima Tobacco use is the single most preventable cause of death among adults and is a significant factor for several mouth, throat, lung and heart diseases. It is also a major contributor to morbidity. Globally, the World Health Organisation (WHO) estimates that tobacco causes about 71% of lung cancer, 42% of chronic respiratory diseases, 20% of global tuberculosis incidence and nearly 10% of cardiovascular diseases. But the issue of smokeless products that contain tobacco has for long been ignored. According to Dr Sheila Ndyanabangi, the tobacco control focal point person at the ministry of Health, schoolchildren are also consuming the products. This is because sometimes the ingredients are written in foreign languages which may not be understood by the consumers. What is smokeless tobacco? There are two basic forms of smokeless tobacco: snuff and chewing tobacco. An article ‘smokeless tobacco and how to quit’ on the website www.cancer.org, says snuff is finely ground tobacco packaged in cans and is sold either dry or moist. The nicotine in the snuff is absorbed through the tissues of the mouth as it is placed between the cheek and gum. Snuff is designed to be both “Smoke-free” and “spit-free” and is marketed as a discreet way to use tobacco. Chewed tobacco comes along as long strands of tobacco leaves that are chewed by the user who thereafter spits out the brown liquid (saliva mixed with tobacco). Types of smokeless tobacco Mouth fresheners: The commonest is Kuber. It is [...]

Cancer-causing chemical found in smokeless tobacco

Source: www.foxnews.com Author: staff A chemical in smokeless tobacco products has been found to cause cancer, according to a new study in animals. The chemical was a strong inducer of oral tumors, the study showed.   While use of smokeless tobacco products has been strongly linked to the development of cancer, no specific chemical in the products had been identified as a strong oral-cancer causing agent until now, the researchers say. The chemical, called (S)-N'-nitrosonornicotine, or (S)-NNN, "is the only chemical in smokeless tobacco known to cause oral cancer," study researcher Silvia Balbo, a cancer researcher at the University of Minnesota, said in a statement. The finding may explain how smokeless tobacco products cause cancer, Balbo said. Balbo said the findings are an affirmation that tobacco products should be avoided. Smokeless tabacco products are already required to carry warning labels saying the products can cause mouth cancer or are not a safe alternative to cigarettes, the Food and Drug Administration says. The most common type of smokeless tobacco product is moist snuff placed in the mouth. Previous studies have suggested that a group of chemicals called nitrosamines, of which (S)-NNN is a member, cause various types of cancer in animals, but no study has looked at the carcinogenicity of (S)-NNNspecifically, the researchers say. Balbo and colleagues administered (S)-NNN to 24 rats. The rats were given (S)-NNN or tap water. The total dose was approximately equivalent to the amount of (S)-NNN to which a smokeless tobacco user would be exposed from [...]

Smokeless tobacco won’t help smokers quit

Source: www.webmd.com Author: Bill Hendrick Smokeless tobacco products -- whether chewed or used as dry or moist snuff -- may increase the risk of heart attack, fatal stroke and certain cancers, says a new policy statement published online in Circulation: Journal of the American Heart Association. "No tobacco product is safe to consume," Mariann Piano, PhD, lead writer of the policy statement and a professor in the department of behavioral health science at the University of Illinois at Chicago, says in a news release. The notion that smokeless tobacco may help reduce the rate of cigarette smoking is based in part on Swedish research, which showed a significant decline in smoking by Swedish men between 1976 and 2002 that corresponded with an increase in the use of smokeless tobacco. But in similar research in the U.S., the opposite was found to be true, the article says. There was no reduction in smoking rates among people who used smokeless tobacco products. Nicotine-Replacement Therapy Piano says that smokers trying to kick the habit might want to try nicotine-replacement therapy, by chewing nicotine gum or using a nicotine patch that can be attached to the skin, rather than using smokeless tobacco products. Piano tells WebMD that most people who use nicotine-replacement therapy do so for short periods of time, and it doesn't appear to be as addictive as smokeless tobacco "because of slower absorption, lower doses of nicotine, greater cost, lack of flavoring, sociocultural influences" or a combination of such factors. She says [...]

2010-09-14T09:06:26-07:00September, 2010|Oral Cancer News|

New types of smokeless tobacco present growing risks for youth: products mistaken for candy

Source: thenationshealth.aphapublications.org Author: Kim Krisberg The decline in the U.S. smoking rate is arguably one of the biggest achievements in the nation’s public health history. But as public health makes inroads, the tobacco industry is pushing back, offering new ways to deliver nicotine and hook lifelong customers. As nonsmoking ordinances sweep across the country, tobacco manufacturers are marketing new smokeless and spitless tobacco products, often selling them as complementary products to cigarettes — pushing the message that such “novel” tobacco products can deliver a nicotine fix whether smoking is allowed or not. Going by brand names such as Orbs, Snus and Taboka, the products are smokeless and spitless, often dissolving in a user’s mouth. For example, Marlboro Snus comes in a teabag-like pouch that a user puts between the cheek and gum and then discards after about 30 minutes. Camel Orbs look similar to small pieces of candy — almost like a Tic Tac — come in flavors such as “fresh” and “mellow,” and dissolve in a user’s mouth. Camel Sticks and Camel Strips also dissolve in a user’s mouth. A recent Camel Snus ad reads “Boldly Go Everywhere” and “Break Free.” While such products have yet to catch on in a significant way in the United States, public health advocates warn not to underestimate the influence of tobacco marketing, especially in regard to young people. They also warn that tobacco companies seem to be portraying the novel products as a “healthier” alternative to cigarettes or as a quitting aid. [...]

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