Tag Archive | "radiotherapy"

Cisplatin aids survival of high-risk head and neck cancer

Friday, February 3, 2012

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Source: www.oncologyreport.com Author: Miriam E. Tucker Adding chemotherapy to radiotherapy improved 10-year survival of resectable head and neck carcinomas among high-risk patients who had microscopically involved resection margins and/or extracapsular spread of disease – but not in high-risk patients who only had tumor in multiple lymph nodes. The findings come from a long-term update and [...]

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Implications of the Oropharyngeal Cancer Epidemic

Wednesday, November 9, 2011

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Source: Journal of Clinical Oncology Chaturvedi et al,1 analyzing specimens back to 1984, validate the long-held hypothesis that infection with human papillomavirus (HPV) has increased oropharyngeal squamous cell carcinoma (OPSCC) incidence in the US. They find the incidence of OPSCC in men—who have higher risks of both HPV-positive and HPV-negative OPSCC than women—similar to that [...]

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EU grants orphan drug status to BioAlliance Pharma’s clonidine Lauriad

Sunday, November 6, 2011

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Source: www.pharmabiz.com Author: staff European Commission has granted orphan drug designation to BioAlliance Pharma SA’s clonidine Lauriad for prevention of radiotherapy-induced oral mucositis in patients with head and neck cancer. Oral mucositis is a very frequent inflammation of the oral mucosa in head and neck cancer patients treated with radio- and chemotherapy (98,000 new patients [...]

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GP96 is over-expressed in oral cavity cancer and is a poor prognostic indicator for patients receiving radiotherapy

Saturday, October 15, 2011

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Source: http://7thspace.com Author: Chien-Yu Lin et al. Oral cavity cancers (ORC) are the most common cancers, and standard treatment is radical surgery with postoperative radiotherapy. However, locoregional failure remains a major problem, indicating radioresistance an important issue. Our previous work has shown that GP96 contributed to radioresistance in nasopharyngeal and oral cancer cell lines. In [...]

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Prevalence and Treatment Management of Oropharyngeal Candidiasis in Cancer Patients: Results of the French Candidoscope Study

Tuesday, September 20, 2011

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Source: RedJournal.org Purpose The aim of this pharmaco-epidemiological study was to evaluate the prevalence of oropharyngeal candidiasis (OPC) in cancer patients treated with chemotherapy and/or radiotherapy. Methods and Materials Signs and symptoms of OPC were noted for all patients. Antifungal therapeutic management was recorded in OPC patients. Patients receiving local antifungal treatments were monitored until [...]

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Palifermin Decreases Severe Oral Mucositis of Patients Undergoing Postoperative Radiochemotherapy for Head and Neck Cancer: A Randomized, Placebo-Controlled Trial

Tuesday, September 20, 2011

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Source: OncologyStat.com TAKE-HOME MESSAGE This randomized, placebo-controlled trial found that weekly palifermin was associated with decreased incidence and duration of severe oral mucositis in patients undergoing postoperative chemoradiotherapy for head and neck cancer. SUMMARY OncologySTAT Editorial Team Combined chemoradiotherapy (CRT) offers improved outcomes after resection of locally advanced head and neck cancer but also increases [...]

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Fighting cancer with scorpions?

Friday, September 9, 2011

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Source: www.foxnews.com Author: Chris Kilham In the fight against cancer, scientists and medical researchers around the world are developing new medicines from seemingly unlikely natural substances. Recent reported developments involve the use of a bacteria found in soil, a poison from a highly toxic scorpion, and the virus that causes herpes. All three demonstrate novel [...]

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Stroke and TIA risk doubled by radiotherapy, study finds

Thursday, August 11, 2011

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Source: www.imt.ie Author: Mary Anne Kenny The risk of transient ischaemic attack (TIA) or ischaemic stroke is at least doubled by head and neck radiotherapy, a problem increasing in urgency as patients survive their malignancies longer, an Australian review of the literature has concluded. Besides case reports, the reviewers found 77 studies of stroke, TIA [...]

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Ischemic Stroke, Transient Ischemic Attack after Head & Neck Radiotherapy

Friday, August 5, 2011

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Source: AHA Journals Author: Chris Plummer, PhD; Robert D. Henderson, PhD; John D. O’Sullivan, MD; Stephen J. Read, PhD Abstract Background and Purpose—Cerebrovascular disease can complicate head and neck radiotherapy and result in transient ischemic attack and ischemic stroke. Although the incidence of radiation vasculopathy is predicted to rise with improvements in median cancer survival, [...]

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HPV related oral cancers continue to increase in the US

Monday, June 6, 2011

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Source: International Medicine News CHICAGO – Human papillomavirus infection was firmly linked to the recent rise in oropharyngeal cancers in the United States, based on data from the National Cancer Institute’s Surveillance, Epidemiology, and End Results program. If current trends continue, the incidence of HPV-related oral cancers will soon surpass that of cervical cancers, senior [...]

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