Tongue and tonsil cancer patients surviving longer

Source: Dr.Biscuspid.com The five-year survival rate for U.S. patients with cancer of the base of the tongue or tonsils doubled between 1980 and 2002, according to a new study in Cancer Causes & Control (January 2012, Vol. 23:1, pp. 153-164). In addition, patients with human papillomavirus (HPV)-related cancers had greater survival rates than those with other oral cancers, and survival was greater for male patients than females regardless of age, according to the study authors, from the New York Eye and Ear Infirmary, the University of Utah School of Medicine, and the University of California, Los Angeles School of Public Health. However, patients with subsequent multiple cancers showed no overall survival improvement. The incidence rates of tongue and tonsil cancers have increased significantly in recent decades in the U.S., particularly among younger patients, the researchers noted. At the same time, a number of studies have shown a strong association between HPV infection and tongue and tonsil cancers. For this study, they used data from the Surveillance, Epidemiology, and End Results (SEER) 1973-2006 registry system to examine changes in survival rates among patients with base of tongue, tonsil, and other tongue cancers in recent decades. The study included 10,704 patients with squamous tongue or tonsil cancer who were at least 20 years old. The researchers separated the patients into those with one primary cancer and those with subsequent multiple cancers, then compared trends using three nonoverlapped periods: 1980-1982, 1990-1992, and 2000-2002. The first group included those with only one primary base of tongue, [...]

Needed: HPV vaccine, simple screening test, for women and men

Source: jhu.edu/~gazette Author: Valerie Mehl, Johns Hopkins Medicine A call to explore a broader use of human papillomavirus vaccines and the validation of a simple oral screening test for HPV-caused oral cancers are reported in two studies by an investigator at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Leading HPV expert Maura Gillison, the first to identify HPV infection as the cause of certain oral cancers and who identified multiple sex partners as the most important risk factor for these cancers, reports her latest work Nov. 3 in the journal Clinical Cancer Research and in a Centers for Disease Control and Prevention monograph. The CDC report on HPV-associated cancers appears online Nov. 3 and in the Nov. 15 supplement edition of Cancer. In the CDC report, believed to be the first and most comprehensive assessment of HPV-associated cancer data in the United States, investigators analyzed cancer registry data from 1998 to 2003 and found 25,000 cancer cases each year occurred at cancer sites associated with HPV infection. In additional analysis, Gillison and colleagues at the National Cancer Institute identified HPV infection as the underlying cause of approximately 20,000 of these cancers. Gillison and her team found that approximately 20,000 cases of cancer in the United States each year are caused by HPV infection. Oral cancers are the second most common type of HPV- associated cancers and are increasing in incidence in the United States, particularly among men. Add to that anal, penile, vaginal and vulvar cancers that are [...]

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