Laser and nanoparticles blow up cancer cells

Source: news.softpedia.com/ Author: Tudor Vieru In a new approach to fighting cancer cells, or cells ridden by several other types of diseases as well, researchers managed to combine the powers of lasers and nanoparticles most efficiently. The method relies on using short bursts of laser light to produce small explosions from gold particles that have been placed inside the targeted cells beforehand. The blasts, which cause no ill-effects to surrounding cells, are highly capable of dismembering the cancerous ones, acting like a “jackhammer” on their targets, and pounding relentlessly, LiveScience reports. Basically, the active elements in this therapy are nanobubbles, which form as the gold particles are subjected to intense, but short, laser pulses. The science group, which is based at the Rice University, was able to determine that the intensity of the lasers could be tuned in two ways, resulting in two different results. The end result could be either clear, bright and small bubbles, that were harmless, or larger explosions that took place inside the cell, which dismembered it. “Single-cell targeting is one of the most touted advantages of nanomedicine, and our approach delivers on that promise with a localized effect inside an individual cell. The idea is to spot and treat unhealthy cells early, before a disease progresses to the point of making people extremely ill,” says RU physicist Dmitri Lapotko. He was also the author of a new study detailing the method, which appears online, in the January 25 issue of the respected scientific journal Nanotechnology. [...]

2010-02-07T09:35:35-07:00February, 2010|Oral Cancer News|

University of Toronto researchers create microchip that can detect type and severity of cancer

Source: www.newswire.ca Author: Press release U of T researchers have used nanomaterials to develop a microchip sensitive enough to quickly determine the type and severity of a patient's cancer so that the disease can be detected earlier for more effective treatment. Their groundbreaking work, reported Sept. 27 in Nature Nanotechnology heralds an era when sophisticated molecular diagnostics will become commonplace. "This remarkable innovation is an indication that the age of nanomedicine is dawning," says Professor David Naylor, president of the University of Toronto and a professor of medicine. "Thanks to the breadth of expertise here at U of T, cross-disciplinary collaborations of this nature make such landmark advances possible." The researchers' new device can easily sense the signature biomarkers that indicate the presence of cancer at the cellular level, even though these biomolecules - genes that indicate aggressive or benign forms of the disease and differentiate subtypes of the cancer - are generally present only at low levels in biological samples. Analysis can be completed in 30 minutes, a vast improvement over the existing diagnostic procedures that generally take days. "Today, it takes a room filled with computers to evaluate a clinically relevant sample of cancer biomarkers and the results aren't quickly available," says Shana Kelley, a professor in the Leslie Dan Faculty of Pharmacy and the Faculty of Medicine, who was a lead investigator on the project and a co-author on the publication. "Our team was able to measure biomolecules on an electronic chip the size of your fingertip [...]

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