Tag Archive | "DNA"

Black raspberries reduce DNA damage in oral cancer survivors

Thursday, April 11, 2013

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Source: www.prweb.com Author: press release New research presented Wednesday, April 10, at the American Association for Cancer Research Annual Meeting 2013 in Washington, DC, suggests that a food-based cancer prevention study aimed at oral cancer survivors was effective at attenuating highly reactive oxygen molecules that can damage DNA and trigger cancer. In the study, a [...]

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Researchers document molecular tumor subtypes of head and neck cancer

Tuesday, March 12, 2013

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Source: www.oncologynurseadvisor.com Author: Kathy Boltz, PhD Head and neck squamous cell carcinoma (HNSCC) is the seventh most common form of cancer in the United States. However, other than an association with the human papillomavirus (HPV), no validated molecular profile of the disease has been established. By analyzing data from DNA microarrays, a study has confirmed [...]

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DNA adducts linked to oral cancer in smokers

Saturday, January 5, 2013

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Source: www.news-medical.net Author: Sarah Guy, medwireNews Reporter Having a high susceptibility to certain types of DNA damage caused by tobacco smoking could significantly increase the risk for oral cancer, show results of a Taiwanese study. Levels of BaP 7,8-diol 9,10-epoxide (BPDE) – a metabolite of Benzo[a]pyrene, an important carcinogen found in cigarette smoke – correlated [...]

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DNA alone inadequate to identify HPV-related cancers

Monday, September 24, 2012

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Source: www.oncologypractice.com Author: Mary Ann Moon Testing for the presence of human papillomavirus DNA alone, especially using polymerase chain reaction methods, is not adequate to identify which head and neck squamous cell carcinomas are caused by the virus, according to two studies published online Sept. 18 in Cancer Research. Identifying HPV-driven malignancies is important because [...]

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Predicting oral cancer

Tuesday, September 11, 2012

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Source: www.dailyrx.com Oral cancers can occur anywhere in the mouth. As with any cancer, the sooner it’s found, the better. A new tool helps doctors know when oral cancer may be in a patient’s future. A recent study finds that a set of molecular markers can help judge which lesions in the mouth are most [...]

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Molecular markers help predict oral cancer progression

Wednesday, August 22, 2012

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Source: DrBicuspid.com August 21, 2012 — A group of molecular markers has been identified that can help clinicians determine which patients with low-grade oral premalignant lesions are at high risk for progression to oral cancer, according to data from the Oral Cancer Prediction Longitudinal Study published in Cancer Prevention Research (August 21, 2012). “The results [...]

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Demystifying the immortality of cancer cells

Sunday, July 8, 2012

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Source: http://medicalxpress.com/ Author: In cancer cells, normal mechanisms governing the cellular life cycle have gone haywire. Cancer cells continue to divide indefinitely, without ever dying off, thus creating rapidly growing tumors. Swiss scientists have discovered a protein complex involved this deregulated process, and hope to be able to exploit it to stop tumor formation in [...]

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Genes May Link Disparate Diseases

Wednesday, May 2, 2012

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Source: The Wall Street Journal Diseases that strike different parts of the body—and that don’t seem to resemble each other at all—may actually have a lot in common. Scientists have identified the genetic basis for many separate diseases. Now, some researchers are looking at how the genes interact with each other. They are finding that [...]

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HPV DNA, E6?I-mRNA expression and p16(INK4A) immunohistochemistry in head and neck cancer – how valid is p16(INK4A) as surrogate marker?

Tuesday, April 17, 2012

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Source: HighWire- Stanford University It has been proposed that p16(INK4A) qualifies as a surrogate marker for viral oncogene activity in head and neck cancer (HNSCC). By analyzing 78 HNSCC we sought to validate the accuracy of p16(INK4A) as a reliable marker of active HPV infections in HNSCC. To this end we determined HPV DNA (HPVD) [...]

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Oral HPV infection affects 7% of the US population

Wednesday, March 14, 2012

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Source: www.onclive.com Author: Ben Leach Approximately 7% of Americans are infected with oral human papillomavirus (HPV), and men are 3 times as likely to be infected as women, according to an analysis that helps define a leading factor in the rise of oropharyngeal cancer. The findings of the HPV prevalence study were presented at the Multidisciplinary Head [...]

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