Antibiotic prescriptions linked to significant delays in head and neck cancer diagnosis

Source: www.healio.com Author: Drew Amorosi Key takeaways: Researchers reported increased rates of antibiotic prescriptions in the 3 months prior to head/neck cancer diagnosis. Antibiotic prescriptions appeared linked to longer time between symptom onset and diagnosis. Approximately 15% of individuals with head and neck cancer received an antibiotic prescription within 3 months of diagnosis, study results showed. Those who received antibiotic prescriptions had significantly longer time to head and neck cancer diagnosis than those who did not receive antibiotics, findings published in JAMA Otolaryngology–Head & Neck Surgery showed. “These patients have been through the health care system for many months without an accurate diagnosis,” Sean T. Massa, MD, assistant professor in the department of otolaryngology — head and neck surgery at Saint Louis University School of Medicine, told Healio. “Prescribing antibiotics is a common practice and was associated with a delay in diagnosis,” he added. “For adults with a neck mass or swelling lasting more than 2 weeks, the most likely cause is a tumor, so patients should be evaluated through further testing and referral to a specialist.” Background Head and neck specialists have observed a steady stream of patients with neck masses mistakenly prescribed antibiotics because symptoms mirror that of infection, Massa said. This occurs despite 2017 guidelines from American Academy of Otolaryngology — Head and Neck Surgery (AAO-HNS) for evaluation of neck mass among adults. The guidelines recommend against prescribing antibiotics without other infectious symptoms. “We wanted to see if patients who received antibiotics took longer to get from [...]

2023-09-02T07:50:29-07:00September, 2023|Oral Cancer News|

Why salivary diagnostics for dental practices?

Source: www.dentistryiq.com Author: Barbara Kreuger, MA, RDH I recently had the opportunity to visit OralDNA Labs and learn more about the process of running salivary diagnostic tests. Admittedly, when I first heard about salivary diagnostics, I didn’t immediately embrace the tests and what they had to offer. I was not convinced that they were necessary, believing they would not change how we treat dental disease. However, we’ve been fortunate to use salivary diagnostics in practice and see the benefits in our patients firsthand. These tests have proven to be a great addition to our prevention tool box. Salivary diagnostics can play an important role in helping us produce high quality outcomes for patients and create awareness of their oral-systemic risk factors. Bacterial identification There are numerous salivary diagnostic tests available. The most widely used test from OralDNA Labs is MyPerioPath, which tests for the 11 pathogens that are known to contribute to periodontal destruction.(1) Once the test reveals which pathogens are contributing to the patient’s periodontal disease, it also offers antibiotic recommendations that target these specific bacteria. When combined with periodontal maintenance visits and patient homecare, this test can lower a patient’s bacterial load, thus increasing positive outcomes. Retesting has shown that this reduction in bacteria can have a dramatic effect. We’ve seen tough cases—patients who were compliant with homecare but still exhibited clinical signs of periodontal disease—that improved dramatically after being treated with the test’s recommended systemic antibiotic. Periodic monitoring with MyPerioPath combined with periodontal maintenance treatment can help [...]

2019-02-08T14:32:58-07:00February, 2019|Oral Cancer News|

Photodynamic therapy targets oral dysplasia, oral bacteria

Source: www.drbicuspid.com Author: Kathy Kincade, Editor in Chief Imagine being able to treat a suspicious lesion on a patient's tongue simply by applying a topical agent, waiting a few minutes, then exposing it to light from a handheld laser or light-emitting diode (LED) device. Imagine being able to treat bacterial and fungal infections in the oral cavity, even periodontal disease, using this same approach. That is the promise of photodynamic therapy (PDT), a minimally invasive technique that first came into medicine in the early 1900s and has been used to treat a plethora of medical conditions, including skin diseases, localized infections, age-related macular degeneration, and premalignant and malignant disorders. "PDT in the oral cavity would utilize a photosensitizing compound and a light source to activate the compound," explained Thomas Mang, PhD, research director in the Laser and Lightwave Research Center at the University at Buffalo School of Dental Medicine. "Traditionally, it has been used in head and neck lesions and oral lesions with a photosensitizer given intravenously. But in applications related to early oral lesions and those involving candida and oral species that may be involved with periodontal disease, we look to apply it topically." Distinct advantages Mang has been investigating PDT disinfection of oral biofilm and previously was involved with the development of PDT for treating cutaneous and other cancers while at Roswell Park Cancer Institute. He sees a bright future for PDT in dentistry, providing more selectivity and flexibility when treating patients with early oral lesions and microbial [...]

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