cheapest acronis true image home 2009 buy pdf converter buying excel 2007 cost of windows server 2008 r2 standard buying screenflow for mac buy autoroute 2011 cheap final cut express 4 cheap autocad 2009 download buy omnipage 17 microsoft office 2010 academic discount buy windows xp home edition upgrade buy windows 7 home premium activation key price of adobe creative suite 5 design premium buy mathworks matlab buy apple iwork 08 price of office 2010 professional plus cost of win xp home edition buy mac os x server 1.0 cheap photoshop cs3 uk buy windows 7 family pack in canada buy apple motion 4 buy windows 7 discount buy microsoft powerpoint 2008 cheap autodesk 3ds max buy autoroute australia buy outlook download microsoft word 2007 product key buy cheap microsoft office 2010 students cheap adobe dreamweaver cs4 price of windows 7

Dysphagia after definitive radiotherapy for head and neck cancer

Mon, Jan 14, 2013

Oral Cancer News

Source: Strahlentherapie und Onkologie

Authors:

Background

Dysphagia is a complication of head and neck cancer patients undergoing radiotherapy (RT). We analysed frequency and severity of swallowing dysfunction and correlated these findings with dose–volume histograms (DVHs) of the pharyngeal constrictor muscles.

Methods

A total of 50 patients treated by radical RT were enrolled. DVHs of constrictor muscles were correlated with acute and late dysphagia and with the items of three quality of life questionnaires.

Results

Mean dose to superior and middle constrictor muscles (SCM, MCM), partial volume of SCM and MCM receiving a dose ≥ 50 Gy dose to the whole constrictor muscles ≥ 60 Gy and tumour location were associated to late dysphagia at univariate analysis. Mean dose to the MCM was the only statistically significant predictor of late dysphagia at the multivariable analysis.

Conclusion

The study shows a significant relationship between long-term dysphagia and mean doses to SCM, MCM, whole constrictor muscles, and oropharyngeal tumour. This finding suggests a potential advantage in reducing the RT dose to swallowing structures to avoid severe dysphagia.

 This article was sourced by The Oral Cancer Foundation and vetted for accuracy and appropriateness.
Print Friendly
Be Sociable, Share!
,

Leave a Reply

You must be logged in to post a comment.