can you take 400 mg of celebrex a day gabapentin 300 mg hard capsules valtrex mg neurontin buy levothyroxine online pharmacy cialis original 20 mg precio viagra en farmacia españa compra levitra viagra generique belgique cual es la mejor pastilla de viagra buy finasteride online no prescription buy proscar cheap avodart and flomax together buy dapoxetine generic inderal no prescription needed cialis generico online españa cialis offerta cialis 20 mg generico prix cialis 20 comprar viagras ciprofloxacin 500 mg tablets uses ciprofloxacin hydrochloride tablets i p 500 mg buying cipro in mexico medicament flagyl 500 mg
priligy 30 mg avis generique zovirax comprimés médicament betamethasone

Cigarette, Cigar, and Pipe Smoking and the Risk of Head and Neck Cancers: Pooled Analysis in the International Head and Neck Cancer Epidemiology Consortium

Mon, Jul 8, 2013

Oral Cancer News

Source: Oxford Journals
Received July 26, 2012.
Accepted February 8, 2013
 

Abstract

Cigar and pipe smoking are considered risk factors for head and neck cancers, but the magnitude of effect estimates for these products has been imprecisely estimated. By using pooled data from the International Head and Neck Cancer Epidemiology (INHANCE) Consortium (comprising 13,935 cases and 18,691 controls in 19 studies from 1981 to 2007), we applied hierarchical logistic regression to more precisely estimate odds ratios and 95% confidence intervals for cigarette, cigar, and pipe smoking separately, compared with reference groups of those who had never smoked each single product. Odds ratios for cigar and pipe smoking were stratified by ever cigarette smoking. We also considered effect estimates of smoking a single product exclusively versus never having smoked any product (reference group). Among never cigarette smokers, the odds ratio for ever cigar smoking was 2.54 (95% confidence interval (CI): 1.93, 3.34), and the odds ratio for ever pipe smoking was 2.08 (95% CI: 1.55, 2.81). These odds ratios increased with increasing frequency and duration of smoking (Ptrend ≤ 0.0001). Odds ratios for cigar and pipe smoking were not elevated among ever cigarette smokers. Head and neck cancer risk was elevated for those who reported exclusive cigar smoking (odds ratio = 3.49, 95% CI: 2.58, 4.73) or exclusive pipe smoking (odds ratio = 3.71, 95% CI: 2.59, 5.33). These results suggest that cigar and pipe smoking are independently associated with increased risk of head and neck cancers.

*This news story was resourced by the Oral Cancer Foundation, and vetted for appropriateness and accuracy.

Print Friendly
Be Sociable, Share!
, ,

Leave a Reply

You must be logged in to post a comment.