buy autocad civil 3d cheap office 2007 download buy word 2010
viagra alternative in india vardenafil hydrochloride 50 mg sildenafil viagra australia customs viagra use in australia where to get viagra australia reason 4.0 software purchase cheap ms outlook 2010 adobe dreamweaver oem rosetta stone arabic used buy ilife 11 uk buy flash cs5.5 online buying microsoft office 2013 with product key purchasing word 2007

Carcinoma of the oral tongue in patients younger than 30 years: Comparison with patients older than 60 years

Wed, Oct 2, 2013

Oral Cancer News

Source: oraloncology.com
Published Online” 07 August 2013.

 

Summary 

Objectives

The incidence of oral tongue squamous cell carcinoma is rising in young patients. This study evaluated the clinical, pathological, and prognostic characteristics of oral tongue squamous cell carcinoma in the under-30-year age group.

Materials and methods

The computerized database of the Department of Otolaryngology-Head and Neck Surgery of a tertiary, university-affiliated medical center was searched for all patients with oral tongue squamous cell carcinoma treated by glossectomy with curative intent in 1996–2012. Data were collected by chart review.

Results

Of the 113 patients identified, 16 (14%) were aged ⩽30transparent.gifyears at presentation and 62 (55%) >60transparent.gifyears. Mean follow-up time was 30transparent.gifmonths. Comparison by age group revealed no sex predilection and no differences in histologic grade or rates of advanced T-stage, perineural and vascular invasion, or nodal extracapsular extension. Rates of node-positive disease were 75% in the younger group and 19% in the older group (ptransparent.gif<transparent.gif0.001). Kaplan–Meier analysis yielded no between-group difference in disease-free or overall survival. Recurrence was documented in a similar proportion of patients (38% and 29.9%, respectively), but half the recurrences in the younger group were distant versus none in the older group (ptransparent.gif=transparent.gif0.01) All younger patients with recurrent disease died within 16transparent.gifmonths of its appearance compared to 50% 3-year disease-specific survival in the older group.

Conclusions

Oral tongue squamous cell carcinoma is more advanced at presentation in younger than in older patients, with higher rates of regional metastases and distant failure. Recurrent disease is more aggressive, with a fatality rate of 100%.

 

 *This news story was resourced by the Oral Cancer Foundation, and vetted for appropriateness and accuracy.

 

 

Print Friendly
Be Sociable, Share!
,

Leave a Reply

You must be logged in to post a comment.