Wart Virus Linked to Head and Neck Squamous Cell Carcinoma: Presented at AHNS
8/22/2006 Chicago, IL John Otrompke Poster 160 - AHNS Human papilloma virus (HPV), the condition which has been suggested as a causative agent in cervical cancer, has also been linked to head and neck squamous cell carcinoma (HNSCC), according to a paper presented here at the 2006 annual meeting of the American Head and Neck Society (AHNS). "The prevalence of HPV is rising worldwide," noted study presenter Jose-Francisco Gallegos-Hernandez, MD, surgeon, head and neck department, Oncology Hospital, Mexico City, Mexico. The poster presented on August 19th reported the results of a study of 118 head and neck cancer patients which found unusually high prevalence of two types of HPV, in particular, HPV type 16 and type 18. HPV type 18 is associated with the development of leucoplasia as a preneoplastic lesion, while type 16 has been associated with a better prognosis in head and neck cancer patients. The researchers identified some strain HPV in 42% of the cases. Of those, HPV type 16 was present 70% of the time. "Some authors say that patients with HPV have a better prognosis, maybe because alcohol and tobacco use are not present in as many patients with HPV," said Gallegos-Hernandez. While the study looked for a link between alcohol and tobacco use (two other oft-cited factors in head and neck cancer) and sexual practices and HPV, none was found, he said. Fifty percent of patients with laryngeal cancer had HPV, he said. HPV type 16 was present in 20% of those with mouth [...]